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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cac5cb25d30005a5d9d6835ca2027edd2680c21b866dcf7faa24b5a79176bc2' 
  AND token = 'FsgMBT/I3suKsFw63Xjo5wwrZWryD2qlsQGRwm4adoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}