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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2245ffe55a2913da5831ca3c388623e7215c769a732c856036afacb2114e9e' 
  AND token = '/v6FOAtbUEADW02wbS2MH/A7XlPaK3aEiecCOhvVXyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}