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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b40b5d9bed96bd577bf39146b6bd1ebbb938eb2dd27086d789688818cc0948' 
  AND token = 'Jmu4WJB5OtgLkTi0qYbyO6j6P1pqNqOD5AN4wbkvubo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}