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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6108abaa5073513c1d386b6d46b82df02db37e555f3bde3dd627f35177b1f79' 
  AND token = 'a0JhIJ/1X6+OiisMc1MQbMibRV/z2Fggitl0z2+vbdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}