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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aae8e96ab7972ea1a35fb3f216000d5d0693f3ba156dffea2ea07d9d435bbbb' 
  AND token = 'nUio4PNa+P2llEG9W6xb8QjCBNd8kL8HEOs+9Mgwdz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}