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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b169b56942f20d61b68c5c0e1bdf0bad33beb0d1be09b5226ce1bc0166ae5c2' 
  AND token = 'y1QQcRV7KP0zor5x9rS/uVUnnHfQvttojr2G40GpZx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}