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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1861e03c74cc1c1901b5f3738e52cdb88e5189712942b6393091a3e8a2beb488' 
  AND token = 'Lfg0htVH86ENMH11i8AAjO/v4qCUM//5zSOvmCZrmAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}