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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2205bf81659d832d77d309852dca41f9ea245fd178a1989c6ee42b2eb017c2' 
  AND token = '6YRzjGUdk4ckV5R7QMNxCW4paUCukVRtrnHNfCL3yR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}