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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f85bc49264efe1ec7bbeee963cfb7eb14f104723bd3a3ad93229c81036ab1ec' 
  AND token = 'JX/1xhSnhHhkmTikkkJSuS3CF9Q+0BoF6iP5ucLqi5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}