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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e9cdb623db1486a99f292869c63a8fdc72103a02780b887bdae6c9dcf6f97f8' 
  AND token = '+nk0mZRac6hL+eDs1QouAyEhwEnlOIPLQVGQ8H3jJAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}