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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35904be11cfdf25b902a2891e7155265539f83b3faf06187cc77e4ca3ae98d0e' 
  AND token = '13Dn8N7DGLU8IyT+v5X48P+zfsoz794mDS/P+rE02Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}