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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '519824d26fc9ac066c97153942d135d73fe0a1ed111f520dde487a9f71e8be35' 
  AND token = 'xW7mbWoW26qjv3Wpxcx8iCBaStwZB7kAz7e/6IZVcTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}