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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4accab824a35f5b027a83e4eda9d59e50cc9b17b8962e2a96a2dcf19c9c0fabc' 
  AND token = 'cquPiRbLq5vMCSKE1l0IWxFwtczMpOjxeGz0cFcdd4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}