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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b0b4fa7fc1527dbc23879e0f9aa895f63d8cabda6c0173e689ed61d2e12904' 
  AND token = 'qS9jIixJDdric1VSXSRkDPqlOSwHjWtEC2UMjvdy/u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}