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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efd863a22930f4afaa10ac8acd23577947b3ab93960a9d2bda72b30b4e38d6c' 
  AND token = 'FD+ua9ClbwPJrf9eUGjONZxzpGd/ABXRaE13B2WzAT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}