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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a0efa1b3539083a61e4ee73a11b8960906cc4e126fed98187bc3341c4ffb54' 
  AND token = 'qXn/BxJ33aN1B+FzMQBC3bHYrMo00f2h8DZHIF83qhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}