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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6874e27295001e6f28dba5e592440c6781a290a95b658f484facd36a1148b374' 
  AND token = 'nnba8KoLeAO+HaOLUS//yAY4H+yfyxDMmwH9OsfQBmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}