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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1cfceed4d9d8d1f542e93357805e346c1bfc18d35a9ba46c9385e047b41f73c' 
  AND token = 'rOdadSkKT9ZlDy46iHN+U48vyVkmdYfEaPv4Ladiqxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}