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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51102e3cdc5cf9dd31afa26f9e4346b6dc53984d533affde717b61abb41f256' 
  AND token = 'Lzhvn5VRZy9CrEW8rI8CvieplI5rB4GnIe7+tW9YELY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}