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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '477eb614deb24f520391dac7d4a6347a3388b54253b04fcb5ea16a87e442c50f' 
  AND token = 'EhDDDuT7a69ApqDS1xa6pTfYoFDeyBiFyfoG2UQXSzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}