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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f839c9f14082fdf510eb693d01036fb2566853f02bfd2ca5031889355e22bd4b' 
  AND token = 'CbVZhHTB4vz4MKCBNlvsJL3arSg/1/1M0Y1+0351aSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}