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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4553ca18a1e174b921e04ad0f811ceec719c514487d07f4d47c1c0feb7578e3' 
  AND token = 'm2GAsPonstjy3tnZDnFvcTg2fYiWdJHdMJIj429vKDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}