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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8af9976d9e5c0f83ecb63c41d004d3b291300a95adc9b1b8a3ef5b828f6e0f8' 
  AND token = 'ZVUW6ihKCW9BKm7M4o35lhYEUACKNBkuQttymHPkTJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}