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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e39f449d0564b93d4e5a098c8c7ddcf7b647537ffece33081f4f6fb4685b720' 
  AND token = 'reGQ1kj8/Ls8uzIeGaO09+n5L2wlv+symGBijwN9k14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}