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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a173b727e463f83966f62718402afcce390b8c0aa98499e311262feb9b69066' 
  AND token = 'rdZvT+t5SaldpZ9axcKTbBgIdEKx+qpX89oVsqMM9ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}