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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ad0f685b99dc1f5a15dfb23b4adf09b49715c49245f4c6fa440816e641858e' 
  AND token = 'BIA2nz/dcg+RbqiXn2OmcQVr4TOWHF31F6Q/fuFjkU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}