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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b78e64a1cd36a2dd137c8307dd88d17d823001e006a602f746e1914989e246' 
  AND token = 'RxEXdekNxuxE49NvPTLx7YiS+G0UqEp1O0abqiRb74I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}