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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e00a20c6c1e3b2277c98de0638615a775d00515eb6fda53f0d86adeb0ac1169' 
  AND token = '01f3Q2vRNQ94RnqwelTFnJ8BmkUq9cH8AKR6jeHW/D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}