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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019b6a19a917f527d0336fa743b5476af99cc02702d649f4799c0b0019d6af5e' 
  AND token = 'MHzVcjeZcd6oFXvULQM4LuKYmOC6TfjXvYw9Q9VSs+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}