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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e43abc60c77efea46f97230cb5530f477b06cb1cffa3fde3dd2cf4081c6b4f8' 
  AND token = '+XHbGrZbD2/Pm0TyBun+KNa7yG9iV2VSnKfryPZWX8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}