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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33526bcb62c7214b293147ddbed9bce4ce5556a65cd2b6a730dae724023644d3' 
  AND token = 'ka57BqwS/mkOeUOLQJC2t/XfBczhy52dL6EkA2wWO6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}