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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508dfe923d04ee815ed7d3b548d2e10f8834684d58825a2d7c7ac6d7f0a77f8d' 
  AND token = 'Htn4RaCk1KVTZW5fWFRIkP8DGS5CynMYTxEyX1XpEFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}