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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '662237265ac95ac6a47e7d0d7e945a525f99a23a262c177aa6a45667a9e56e50' 
  AND token = 'YcGZPWqlndSTnqHQHRcKrTFHD5sjj7oGS+AHgAZxVw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}