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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72377b900556f6a0dd87436058323a1b1a18d3d4e0a366cd2ea1fbcbbb4c3a20' 
  AND token = 'VqtofyhU2v2BJZXbR6RgpV20Psf5ouzEO91i5XzwyaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}