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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e5a15f349a6c806fdacc4463a71e09bbe6ade4030b37bb9f5513cd96d3a794' 
  AND token = 'RWg+1sVh8h2SiaWWwVih8WClWfxLYMst12PIeRFI+h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}