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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '586500828a1cca2802802b1d7ce02193b92b0cbe06e16dd05f8ce2a72fe4e724' 
  AND token = 'pKjx95h6z3HzKyRKN3hgkR/rw8jdC4E2DsCgiC/NsFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}