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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3020451ccbf02e8b8af63347e8c5f812e2c4dad84e10f28a8a5bb0196ec56624' 
  AND token = 'TmxXXAP84xChCF10w+ZAjYeNPWOBFCvyJf1v55a3A3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}