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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb020651aa95dfc415b3bfcd4311b146b88a91b02acde0dca5e0c8531162067' 
  AND token = 'o2FOdGfHzXYVerdy+n9obVGdPKjvlO4cir9YeIlzDGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}