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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d69d9ea0571522e3774db0fbecec53644f544a7f8d58b434c804ca450153444' 
  AND token = 'vqbiMN04I9iiGwJky2FIDkqzdPhk+bRGYO56m1Rs2/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}