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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a5efa18ad745450b2677a96794b4a8ad2f1a5ead21c4d220c40f1ce0c20612' 
  AND token = 'TiPoi6mpp21m3YBeDR6AaoOUYsUwiJfEMcLoAuKR0Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}