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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65086787746beeeb2edb1c31cdbfb2fece0c100ddb1f19493345b2a1c34970b0' 
  AND token = 'np+whF8+T9QAVi1TYMb1kvryvQd9BxF3XxSX4nWueVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}