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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59cb010615123e4dc7065f8b20b46ab9176e72c86f101fd5891900787e1b1202' 
  AND token = 'NwdIjb85hECLOE+3Twln22Gp9HITBgOu+pAKQwWNXgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}