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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b77ff13d174f684574187e302aad2ee509bb8dad00a9d3f936860f366d16702' 
  AND token = 'XQllNkuwOys28osi6DOiONTc2nsVoKQLVB8hwhLP8Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}