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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5215d124c4e878207bc356802ce1b6d593d9f57f0b700df9484d915cb5eb027' 
  AND token = 'cZYlL0ia4RHl8kxK/AcyRhCwB+25cs36CS2cySflm7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}