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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eab85fd1855edc39e9b816aee60271e7c29d0fa8e37e7bf6f1a6d3bf109447d' 
  AND token = 'AWVpK7aV+N3ykv/ub1lILoe9ZFuaarokBSsUAgLh0Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}