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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b46b67b6c27c9b0d57c5a8a429e96d759d1b3772d85d8de03f509df612f0ec' 
  AND token = 'Njwgwy4zt/ocqpgJnXL1SW31OcKeIBpja0UnlCVI0cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}