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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59369d40fe38d527bc434b18d4499bb769a7e6d788386e4a56a41064b36b0f46' 
  AND token = 'nWujZI0jzTNY3LX0cZGbNwlf70PQwqX4KRD3MQGvfRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}