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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '815473da257cee448f2bc381cf0d5cd212276ac8fb8f13e60c40bc35cb4fed05' 
  AND token = 'Crmvx0cUhx4MW2cKteCQRvnrjhIgrg20KuMVJ6GtRsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}