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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c993cbec595ba4e61b5d9fa3a7fc5e44a4a6514135295a5b59db01a3326a5966' 
  AND token = '7OxEODYiyPNuHVluTVCRKNtdbyWBH+kPjBNY2cxSex0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}