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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0bb885142db4e5d4e97f61556eec0eeccdacd3216da03db2fce1c19a565c12' 
  AND token = 'aTe4BTwlJquFstIBhMrp2YG3QdnvETZMLSrek8zksEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}